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Ascorbyl Glucoside
AKA “129499-78-1, L-Ascorbic acid 2-glucoside, AA2G, 2V52R0NHXW, DTXSID50926423, Brightening, skin whitening, RefChem:58140, GlyTouCan:G32886OM”
Antioxidant
Ingredient Facts
Ascorbyl glucoside
AKA: 129499-78-1, L-Ascorbic acid 2-glucoside, AA2G, 2V52R0NHXW, DTXSID50926423, Brightening, Skin whitening, RefChem:58140, GlyTouCan:G32886OM
Antioxidant · Antioxidant · EWG: 1
Synthetic
Antioxidant
Vitamin C
Clean
2-O-alpha-D-Glucopyranosyl-L-ascorbic acid
Formula
C12H18O11
Mol. Weight
338.26
CAS #
129499-78-1
Form
Powder
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
Traditional Use
Created in the 1990s as a stable, water-soluble form of vitamin C designed to provide antioxidant benefits while maintaining longer shelf life than pure ascorbic acid in cosmetic formulations.
Skin Types
●all-skin-types, gentle
Best For
Dullness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
ewg-1
medical-approval
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Ascorbyl Glucoside
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Sodium Ascorbyl Glucoside
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ascorbyl Glucoside
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Effects of Sargassum thunbergii Extract on Skin Whitening and Anti-Wrinkling through Inhibition of TRP-1 and MMPs.
Gam DH, Park JH, Hong JW, Jeon SJ, Kim JH et al.
Molecules (Basel, Switzerland), 2021
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Safety Assessment of Ascorbyl Glucoside and Sodium Ascorb...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, Daniel C Liebler, James G Marks + 6 more
International journal of toxicology, 2025
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Safety Assessment of Ascorbyl Glucoside and Sodium Ascorb...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, Daniel C Liebler, James G Marks + 6 more
International journal of toxicology, 2025
→
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics.
Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC et al.
International journal of toxicology, 2025
→
Safety Assessment of Ascorbyl Glucoside and Sodium Ascorbyl Glucoside as Used in Cosmetics.
Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC et al.
International journal of toxicology, 2025
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evid...
Sidharth Sonthalia, Deepashree Daulatabad, Rashmi Sarkar
Indian journal of dermatology, venereology and leprology, 2016
→
Glutathione as a skin whitening agent: Facts, myths, evidence and controversies.
Sonthalia S, Daulatabad D, Sarkar R
Indian journal of dermatology, venereology and leprology, 2016
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR